Serum alanine aminotransferase in skeletal muscle diseases

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Serum alanine aminotransferase in skeletal muscle diseases.

Although elevation of the levels of serum alanine aminotransferase (ALT) following liver injury is well known, confusion exists concerning skeletal muscle injury as the cause of this rise. We reviewed the records of 16 patients who had muscle necrosis without evidence of liver disease. The patients were divided into three groups: extreme exercise, polymyositis, and seizures. All patients exhibi...

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Effects of Carbamazepine and Valproate on Serum Aspartate Aminotransferase, Alanine Aminotransferase and Gamma - Glutamyltransferase in Children

INTRODUCTION Epilepsy is one of the most common neurological diseases in childhood and adolescence. Carbamazepine (CBZ) and valproate (VPA) have been widely used as the first generation of antiepileptic drugs (AED). AIM The aim of the study has been to evaluate and compare the effect of CBZ and VPA monotherapy on aspartate aminotransferase (AST), alanine aminotransferase (ALT) and gamma-gluta...

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Performance of a reflectometric technique for serum alanine aminotransferase determinations

The Ames Seralyzer uses solid phase chemistry coupled with reflectance spectroscopy to measure levels of serum alanine aminotransferase (serum ALT). The study reported here was carried out to evaluate the performance of the Seralyzer method compared to conventional analyses carried out on a Coulter Dacos discrete random access analyser using Boehringer (BCL) reagents conforming to SCE specicati...

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ژورنال

عنوان ژورنال: Hepatology

سال: 2005

ISSN: 0270-9139,1527-3350

DOI: 10.1002/hep.20548